• Sep 13, 2021
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Provigil is a central nervous system stimulant used for a variety of conditions, which we will go into more detail about shortly. It first came into use in the UK in 2002 and has since become a popular medication, with £2.7 million spent on it each year. It has been approved by the Medications and Healthcare products Regulatory Agency (MHRA) and is available with a prescription on the National Health Service (NHS). Despite being a Schedule IV controlled drug in the US, it has a lower status of 'POM' (Prescription Only Medication) here in the UK. Not everyone is able to get a prescription from a primary care provider such as a GP or a secondary care team such as a specialist hospital consultant. If you are struggling to get a prescription yourself, you can buy Provigil online from our UK based pharmacy without the need for a consultation or prescription.

What is Provigil 200 mg Used For?

As we mentioned before, Provigil tablets are licenced for a range of conditions, and they are also prescribed off-label for a number of uses which we will explain now. People most commonly use Provigil 200 mg for narcolepsy and sleep disorders such as obstructive sleep apnoea and shift work disorder. Narcolepsy is a rare neurological disorder which is characterised by suddenly falling asleep without an apparent reason. It can also cause people to lose muscle tone and collapse unexpectedly, which can be dangerous, for example if the individual hits their head, and it can also be scary for others around them. The condition is not fully understood, but it is thought to be caused by a lack of the neurotransmitter orexin, also called hypocretin, due to certain cells in the body mistakenly attacking the receptors which produce it. Orexin promotes wakefulness and is an essential part of our sleep-wake cycle. People's sleep-wake cycle can also be disrupted by shift work, particularly when people work night shifts or a mixture of day and night shifts from week to week, so the medication can be useful for resetting this disruption and staying awake and alert in the day. People commonly use Provigil for ADHD (attention deficit hyperactivity disorder) however it is not fully understood how this works. ADHD is a neurodevelopmental disorder which has cognitive and behavioural symptoms, including hyperactivity inattentiveness, and impulsivity. Some people do not have symptoms of hyperactivity, and in this case the diagnosis is called ADD (attention deficit disorder). People also use Provigil for studying as it improves concentration and wakefulness which can be useful when assignments are due or when preparing for exams. Research into this has mixed results, however anecdotal evidence has shown that many students benefit from it.

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How Does Provigil Work?

Provigil tablets are central nervous stimulants which means they increase activity in certain regions of the brain. The central nervous system is comprised of the brain and spinal cord and the nerves extend to the peripheral nervous system throughout the body. Nerve cells are called neurons and they transmit information via electrical and chemical signals, and this information controls everything we do including functional activity such as movement and cognitive activity such as emotional regulation and concentration. Information travels from neuron to neuron, and there is a miniscule gap in between each one called a synapse, and this is where the majority of receptors are. These signals are regulated by chemicals called neurotransmitters and they can either be excitatory (increase electrical activity) or inhibitory (reduce electrical activity). The Provigil ingredients (modafinil) are thought to bind to dopamine receptors and as the medication is an agonist for these receptors, when it binds to them it stimulates them to release the neurotransmitter dopamine. It also prevents the reuptake of dopamine, and both of these actions means there will be more of the neurotransmitter in your system. Dopamine is involved with motivation, feelings of happiness, and alertness. The process also indirectly increases the levels of orexin which improves wakefulness.

How Long Does Provigil Last?

Provigil tablets are absorbed quickly after being ingested. They enter the gastrointestinal (GI) tract where they pass into the cardiovascular system, cross the blood brain barrier to enter the brain where they exert their effects. The medication has a high bioavailability of over 80% which means that less than 20% of it is lost after first pass metabolism on its way from the GI tract to the brain. The level of absorption is the same whether it is taken with food or on an empty stomach. It reaches peak plasma concentration after around 2 to 3 hours, and you will start to feel the Provigil effects after around 1 hour. The elimination half-life is on average 11 hours; however, this can vary from person to person depending on factors such as your height and weight, and your rate of metabolism. The elimination half-life refers to the amount of time it takes for half of the medication to be metabolised and eliminated from the body, via the liver and kidneys. This means that it will be detected in your system for at least twice the amount of this time. If you want to read some more anecdotal evidence of how it feels before you buy Provigil 200 mg online, you can find reviews on our website.

Provigil Dosage Information

The exact dosage will depend on what you are taking the medication for. Provigil 200 mg is the usual starting dose for most conditions, although lower doses may be used for certain groups. Provigil 100 mg may be advised if higher doses are contraindicated or if you are an elderly patient. The maximum dosage will also vary from condition to condition, but it should never exceed 400 mg per day. If you are taking it for narcolepsy, then you should take your recommended dose once in the morning and once in the afternoon. Similarly, if you are taking it for ADHD then you should take your first dose when you wake up and you next dose in the afternoon or evening. If you are taking Provigil for studying, you can take 1 tablet about an hour before you need it to start working or when you start studying. It is always wise to take the lowest possible effective dose to minimise any unpleasant side effects, which we will explain in more detail soon. The tablets should always be swallowed whole and taken with a glass of water or juice, and never crushed or chewed. If the medication is crushed, then too much could enter your system at once which could be dangerous. If you are taking multiple doses, then you should ensure that you space the doses evenly throughout the day to make sure it does not build up in your system.

Side Effects

Like with every medication, Provigil has the potential to cause side effects. Luckily, not everyone who takes the medication experiences any, and for those that do they are usually mild and go away on their own after a short period of time. Some of the more common Provigil side effects include:

  • Feeling sick or vomiting
  • A dry mouth
  • Reduced appetite
  • Stomach ache
  • Constipation
  • Fast heart rate

If you experience any of the above side effects, you do not need to stop taking the medication. If you are finding them particularly bothersome or they do not resolve on their own, you can always book a consultation and ask your GP for advice or alternative medication. Very rarely, some people experience serious side effects. If you experience any of the following, then you should stop taking the medication and seek medical advice:

  • Difficulty breathing
  • High blood sugar levels
  • High or low blood pressure
  • Muscle weakness
  • Irregular periods

The above list is not exhaustive and if you are unsure whether any of the side effects apply to you, then you should seek professional advice. Again, this is very rare, some people experience a severe allergic reaction after taking Provigil tablets, called anaphylaxis, or anaphylactic shock. If your throat starts to close up or you get swelling of the face and lips, then you should go to A&E immediately.

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Is Provigil the Same as Modafinil?

Provigil is the brand name of a medication containing the active ingredient modafinil. The medication was first developed by a French pharmaceutical company called Lafon and sold under the brand name Modiodal. Lafon had the patent for the medication and had exclusive rights to sell it as they spent a lot of time and money developing it over years of rigorous clinical trials. Pharmaceutical companies are allowed to own patents for 17 years on average and when the patent runs out, other companies can start to manufacture and sell it as generic medication and market it under their own name. The rights to the patent of this particular medication, however, was leased by a US pharmaceutical company called Cephalon in 1998 and they then had exclusive rights to sell it under the brand name Provigil until 2012. Since then, it has been sold by other companies under various names, including modafinil UK. So! In conclusion, yes, they are the same and they have exactly the same active ingredient with the same chemical make-up, and they are produced to the same safety standards set out by the governing body of each country, which is the MHRA in the UK. As it has been used for the longest amount of time in the US and the UK it is the most well-known brand and tends to be the most trusted, but this also means it is the most expensive. You can buy cheap Provigil from our pharmacy, because we believe that high quality products should be affordable regardless of brand name.

Is Provigil safe for everyone?

Provigil 100 mg is safe for most people, however there are certain medications which do not mix. Some Provigil interactions to be aware of include the following:

  • Other medications containing the active ingredient modafinil
  • Other nootropics UK - including herbal supplements
  • Any other central nervous stimulant

There are also certain groups who should avoid taking Provigil. If any of the following apply to you then you should seek medical advice before taking this medication:

  • You have a psychotic illness or mania
  • You have depression
  • You have had a heart attack before
  • You have angina
  • You have high blood pressure
  • You are pregnant or breastfeeding

This list is not exhaustive and if you have any concerns about taking this medication then you should speak to your GP before taking it.

Before You Buy Provigil

Before you buy Provigil there are some considerations that you may want to take on board. Provigil has many benefits, and as we mentioned earlier it can be used to treat a range of disorders and it can be used as a cognitive enhancer. But it is important to consider whether it is the best medication to suit your needs. Some people may prefer to use natural supplements such as caffeine or gingko biloba, the latter of which has been used for centuries as a natural remedy. Both are natural nootropics and are associated with increased energy and concentration. Provigil long term side effects have not been extensively studied, so it is difficult to say whether it is suitable as a long-term medication. Having said that, natural nootropics have had very few clinical trials whatsoever, and their efficacy cannot be guaranteed.

Buy Provigil online

Despite its POM status, we have made is possible to buy Provigil online. We understand that it is not always easy to get an appointment with your GP and even if you do, they are not always sympathetic to your needs and can make you jump through hoops just to get the medication that is right for you. You can order Provigil from our online, UK based pharmacy by visiting We have a range of medications to suit your needs and we ship all of our orders quickly and in plain packaging for discretion. Contact us if you have any questions!

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